Abnormal lipid metabolism and atherosclerosis: a new perspective on organelle function regulation and ferroptosis

Abnormal lipid metabolism and atherosclerosis: a new perspective on organelle function regulation and ferroptosis

BackgroundAtherosclerosis (AS), characterized by lipid accumulation, contributes significantly to global cardiovascular morbidity. Ferroptosis, an iron-dependent form of cell death triggered by lipid peroxidation, is emerging as a critical player in AS progression. Therefore, our study seeks to eluc...

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Bibliographic Details
Main Authors: Xize Wu, Yuxi Huang, Jiaqi Ren, Xue Pan, Qiuying Wu, Qicheng Cai, Ruiying Wang, Teng Feng, Shan Gao, Bo Wang, Meijia Cheng, Yue Li, Lihong Gong
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Immunology
Subjects:
atherosclerosis
ferroptosis
bioinformatics
machine learning
mitochondrion
lysosome
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1642984/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2025.1642984/full

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