Application of family whole-exome sequencing for prenatal diagnosis—an analysis of 357 cases

Application of family whole-exome sequencing for prenatal diagnosis—an analysis of 357 cases

ObjectiveTranslation of fertility risks through whole-exome sequencing of family lines to identify variants that explain patient’s clinical phenotypes.Methods1. Using techniques such as amniotic fluid, chorionic villus, or umbilical cord blood sampling, intact fetal cells were extracted for cell cul...

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Bibliographic Details
Main Authors: Yijun Ge, Huizhen Yuan, Yao Yu, Junfang Xiao, Danping Liu, Yongbao Peng, Ying Liu, Shuhui Huang, Bicheng Yang, Yongyi Zou, Yanqiu Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Medicine
Subjects:
whole exome sequencing
prenatal diagnosis
structural abnormalities
genetics
ultrasound technology
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2025.1529894/full
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https://www.frontiersin.org/articles/10.3389/fmed.2025.1529894/full

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