Exogenous BMI1 expression aggravates oral squamous cell carcinomas in tongue epithelia

Exogenous BMI1 expression aggravates oral squamous cell carcinomas in tongue epithelia

Oral squamous cell carcinoma (OSCC) is characterized by aggressiveness and a poor prognosis, in part because most patients are diagnosed during the later stages of the disease. B cell-specific Moloney murine leukemia virus integration site 1 (BMI1), part of polycomb repressive complex 1 (PRC1), is a...

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Bibliographic Details
Main Authors: Jorge Baquero, Xiao-Han Tang, Daniel Galke, Theresa Scognamiglio, Tuo Zhang, Dawson Miller, Qiuying Chen, Steven Gross, Lorraine J. Gudas
Format: Article
Language:English
Published: Elsevier 2025-04-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Epigenetics
Oral squamous cell carcinoma
HIF1α
Metabolic reprogramming
SOX9
Transcriptional regulation
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558625000259
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