Exploring global natural product databases for NLRP3 inhibition: Unveiling novel combinatorial therapeutic strategy for hidradenitis suppurativa

Exploring global natural product databases for NLRP3 inhibition: Unveiling novel combinatorial therapeutic strategy for hidradenitis suppurativa

Background: Hidradenitis suppurativa (HS) is a chronic inflammatory skin condition of the terminal hair follicle, which can present in sporadic, familial, or syndromic forms. The exact pathogenesis of HS remains elusive, posing a challenge for the development of effective treatments. Among the vario...

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Main Authors: Muhammad Suleman, Abduh Murshed, Abrar Mohammad Sayaf, Abbas Khan, Salman Ali Khan, Paola Maura Tricarico, Chiara Moltrasio, Abdelali Agouni, Kar Kheng Yeoh, Angelo Valerio Marzano, Sergio Crovella
Format: Article
Language:English
Published: Elsevier 2025-04-01
Series:Journal of Infection and Public Health
Subjects:
Hidradenitis suppurativa
NLRP3
Drug screening
Molecular dynamics simulation
Online Access:http://www.sciencedirect.com/science/article/pii/S1876034125000462
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