Early control of cochlear viral load limits cochlear inflammation and prevents virus-induced sensorineural hearing loss

Early control of cochlear viral load limits cochlear inflammation and prevents virus-induced sensorineural hearing loss

Abstract Human cytomegalovirus (HCMV) is the most common viral infection acquired in utero and a leading cause of neurodevelopmental abnormalities, including sensorineural hearing loss (SNHL). In previous studies using a murine model of HCMV induced SNHL, hearing loss was correlated with virus-induc...

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Bibliographic Details
Main Authors: Matthew D Smith, Maria C. Seleme, Tatiana Marquez-Lago, Jiung-Wen Chen, Michael Mach, William J Britt
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Journal of Neuroinflammation
Subjects:
Hearing loss
Congenital cytomegalovirus infection
Inner ear inflammation
Viral load
Online Access:https://doi.org/10.1186/s12974-025-03416-4
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https://doi.org/10.1186/s12974-025-03416-4

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