Total Synthesis and Stereochemical Assignment of Alternapyrone

Total Synthesis and Stereochemical Assignment of Alternapyrone

Alternapyrone, a bioactive polyketide produced by the fungal host <i>Aspergillus oryzae</i>, is biosynthesized by a polyketide synthase encoded by the <i>alt1-5</i> gene cluster. Despite its known bioactivity, the stereochemical configuration of the three stereogenic centers...

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Bibliographic Details
Main Authors: Hui Zhang, Jiaxuan Feng, Di Wang, Bencan Tang, Chao Xu, Tao Ye
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Molecules
Subjects:
total synthesis
natural products
absolute configuration
prediction
Online Access:https://www.mdpi.com/1420-3049/30/7/1597
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