Advances in the Application of CRISPR-Cas-Based Detection Systems for Safety Monitoring and Control in the Food Supply Chain
As societal demands for food production and regulation continue to rise, foodborne viruses have become a significant food safety risk. CRISPR-Cas is a gene-editing technology that employs RNA-guided Cas nucleases to achieve precise, site-specific modifications within the genome. This review explores...
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| Format: | Article |
| Language: | English |
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Academy of National Food and Strategic Reserves Administration
2025-07-01
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| Series: | Liang you shipin ke-ji |
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| Online Access: | http://lyspkj.ijournal.cn/lyspkj/article/abstract/20250420 |
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| _version_ | 1850032680099381248 |
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| author | WAN Wen-yuan ZHANG Feng LIU Zhi-yong ZHAO Yu |
| author_facet | WAN Wen-yuan ZHANG Feng LIU Zhi-yong ZHAO Yu |
| author_sort | WAN Wen-yuan |
| collection | DOAJ |
| description | As societal demands for food production and regulation continue to rise, foodborne viruses have become a significant food safety risk. CRISPR-Cas is a gene-editing technology that employs RNA-guided Cas nucleases to achieve precise, site-specific modifications within the genome. This review explores the
progress and applications of CRISPR-Cas detection systems in identifying foodborne viruses. It explains the working principles of the CRISPR-Cas system in nucleic acid amplification, signal detection, and amplification, highlighting its advantages in terms of sensitivity, specificity, and rapid response when detecting foodborne viruses in food samples. CRISPR-Cas-based detection methods significantly improve detection efficiency, providing valuable technical support for food industry monitoring. The review also discusses strategies, such as developing industry standards and fostering collaborative efforts to advance the
application of this technology in securing food supply chains. It addresses challenges, including system complexity and a lack of standardization in CRISPR-Cas food safety testing. It also envisions its potential to enhance food safety risk management and regulatory efficiency. This review offers theoretical insights and practical guidance for applying CRISPR-Cas detection systems in food safety. |
| format | Article |
| id | doaj-art-10a21cd165a94fdf8526a122bab42d98 |
| institution | DOAJ |
| issn | 1007-7561 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Academy of National Food and Strategic Reserves Administration |
| record_format | Article |
| series | Liang you shipin ke-ji |
| spelling | doaj-art-10a21cd165a94fdf8526a122bab42d982025-08-20T02:58:33ZengAcademy of National Food and Strategic Reserves AdministrationLiang you shipin ke-ji1007-75612025-07-0133414114710.16210/j.cnki.1007-7561.2025.04.019Advances in the Application of CRISPR-Cas-Based Detection Systems for Safety Monitoring and Control in the Food Supply ChainWAN Wen-yuan0ZHANG Feng1 LIU Zhi-yong2 ZHAO Yu3College of Life Sciences, Shanghai Normal University, Shanghai 200234, ChinaShanghai Jinshan District Market Supervision and Administration Bureau, Shanghai 200540, China Shanghai Xuhui Center for Disease Prevention and Control, Shanghai 200237, ChinaCollege of Life Sciences, Shanghai Normal University, Shanghai 200234, ChinaAs societal demands for food production and regulation continue to rise, foodborne viruses have become a significant food safety risk. CRISPR-Cas is a gene-editing technology that employs RNA-guided Cas nucleases to achieve precise, site-specific modifications within the genome. This review explores the progress and applications of CRISPR-Cas detection systems in identifying foodborne viruses. It explains the working principles of the CRISPR-Cas system in nucleic acid amplification, signal detection, and amplification, highlighting its advantages in terms of sensitivity, specificity, and rapid response when detecting foodborne viruses in food samples. CRISPR-Cas-based detection methods significantly improve detection efficiency, providing valuable technical support for food industry monitoring. The review also discusses strategies, such as developing industry standards and fostering collaborative efforts to advance the application of this technology in securing food supply chains. It addresses challenges, including system complexity and a lack of standardization in CRISPR-Cas food safety testing. It also envisions its potential to enhance food safety risk management and regulatory efficiency. This review offers theoretical insights and practical guidance for applying CRISPR-Cas detection systems in food safety. http://lyspkj.ijournal.cn/lyspkj/article/abstract/20250420crispr-cas detection systemfoodborne virusesnucleic acid detectionfood safetyfood business monitoring |
| spellingShingle | WAN Wen-yuan ZHANG Feng LIU Zhi-yong ZHAO Yu Advances in the Application of CRISPR-Cas-Based Detection Systems for Safety Monitoring and Control in the Food Supply Chain Liang you shipin ke-ji crispr-cas detection system foodborne viruses nucleic acid detection food safety food business monitoring |
| title | Advances in the Application of CRISPR-Cas-Based Detection Systems for Safety Monitoring and Control in the Food Supply Chain |
| title_full | Advances in the Application of CRISPR-Cas-Based Detection Systems for Safety Monitoring and Control in the Food Supply Chain |
| title_fullStr | Advances in the Application of CRISPR-Cas-Based Detection Systems for Safety Monitoring and Control in the Food Supply Chain |
| title_full_unstemmed | Advances in the Application of CRISPR-Cas-Based Detection Systems for Safety Monitoring and Control in the Food Supply Chain |
| title_short | Advances in the Application of CRISPR-Cas-Based Detection Systems for Safety Monitoring and Control in the Food Supply Chain |
| title_sort | advances in the application of crispr cas based detection systems for safety monitoring and control in the food supply chain |
| topic | crispr-cas detection system foodborne viruses nucleic acid detection food safety food business monitoring |
| url | http://lyspkj.ijournal.cn/lyspkj/article/abstract/20250420 |
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