Intra-Bone Marrow Administration of miR-140-3p Improves Bone Metabolism in a Growing Senescence-Accelerated Mouse Prone 6 Strain

Intra-Bone Marrow Administration of miR-140-3p Improves Bone Metabolism in a Growing Senescence-Accelerated Mouse Prone 6 Strain

<b>Background</b>: Our previous study demonstrated that miR-140-3p induced osteocalcin expression in osteoblastic MC3T3-E1 cells. In this study, we investigated the direct effects of miR-140-3p on bone turnover in senescence-accelerated mice. <b>Methods</b>: In order to evalu...

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Bibliographic Details
Main Authors: Hironobu Katsuyama, Kazue Tanda, Kumiko Terada, Shigeko Fushimi, Takeshi Yoda, Vitalii Katsuyama, Tsutomu Nohno
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Biomedicines
Subjects:
miR-140-3p
senescence-accelerated mice prone 6 strain
lipid nanoparticles
flotillin 2
bone histomorphometry
Online Access:https://www.mdpi.com/2227-9059/13/4/883
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