BCG Vaccination Potentially Modulates the Transcriptome of Infant CD4 T Cells in Addition to Age-Dependent Immune Ontogeny-Associated Changes

BCG Vaccination Potentially Modulates the Transcriptome of Infant CD4 T Cells in Addition to Age-Dependent Immune Ontogeny-Associated Changes

Background: The Bacille Calmette–Guérin (BCG) vaccine is part of the Extended Programme on Immunization (EPI) and as such is generally administered at birth. The global introduction of BCG not only protected many vaccinated infants against severe complications of tuberculosis but also resulted in ma...

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Bibliographic Details
Main Authors: Vidya Vijayan Karuvan Kandiyil, Eunchong Kang, Emily Coates, Portia Kamthunzi, Gerald Tegha, Mina Hosseinipour, Di Wu, Fei Zou, Kristina De Paris
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Vaccines
Subjects:
infant CD4 T cell transcriptome
immune ontogeny
BCG vaccination
signaling pathways
Online Access:https://www.mdpi.com/2076-393X/13/7/706
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