Shikonin Induces Autophagy and Apoptosis in Esophageal Cancer EC9706 Cells by Regulating the AMPK/mTOR/ULK Axis

Shikonin is a plant medicine extracted from Lithospermum, which dominate influential antioxidant and antitumor effect. Here, we report that shikonin was capable of inducing human esophageal cancer EC9706 cell apoptosis and autophagy, in a time- and dose-dependent manner. Shikonin exposure repressed...

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Bibliographic Details
Main Authors: Junli Zhang, Jiayi Guo, Biao Gu, Fen Wang, Yi Li, Ling Shang, Wendi Jiang, Junrao Ma, Wenjuan Wu
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:Analytical Cellular Pathology
Online Access:http://dx.doi.org/10.1155/2024/7752299
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