Changes in serum levels of Chitinase protein-40 in children with Kawasaki disease and its clinical significance

Changes in serum levels of Chitinase protein-40 in children with Kawasaki disease and its clinical significance

Abstract Objectives Kawasaki disease (KD) is an acute immune-mediated vasculitis primarily affecting coronary arteries, with limited specific diagnostic biomarkers available. Chitinase protein-40 (YKL-40), a glycoprotein secreted by neutrophils and macrophages, has been associated with vascular infl...

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Bibliographic Details
Main Authors: Yalin Liu, Shan Sun, Baolong Yu, Qianyun Wang, Hui Liu, Xianli Shao, Huafeng Zhao
Format: Article
Language:English
Published: BMC 2025-05-01
Series:BMC Pediatrics
Subjects:
Kawasaki disease
Coronary artery lesion
Chitinase protein-40
Interleukin-6
Diagnostic biomarkers
Online Access:https://doi.org/10.1186/s12887-025-05721-6
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https://doi.org/10.1186/s12887-025-05721-6

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