The Potential of PD-1 and PD-L1 as Prognostic and Predictive Biomarkers in Colorectal Adenocarcinoma Based on TILs Grading

The Potential of PD-1 and PD-L1 as Prognostic and Predictive Biomarkers in Colorectal Adenocarcinoma Based on TILs Grading

Aim: Colorectal cancer (CRC) is a prevalent malignancy with a high mortality rate. Tumor-infiltrating lymphocytes (TILs) play a crucial role in the immune response against tumors. Programmed death-1 (PD-1) and programmed death-ligand 1 (PD-L1) are key immune checkpoints regulating T cells in the tum...

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Bibliographic Details
Main Authors: Nur Rahmah Rasyid, Upik Anderiani Miskad, Muhammad Husni Cangara, Syarifuddin Wahid, Djumadi Achmad, Suryani Tawali, Mardiati Mardiati
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Current Oncology
Subjects:
colorectal cancer
tumor infiltrating lymphocytes
PD-1
PD-L1
immunotherapy
biomarkers
Online Access:https://www.mdpi.com/1718-7729/31/12/552
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