Combination of p-coumaric acid and lactoferrin ameliorates cognitive deficits through suppressing C/EBPβ/AEP pathway and modulating intestinal flora in APP/PS1 mice

Combination of p-coumaric acid and lactoferrin ameliorates cognitive deficits through suppressing C/EBPβ/AEP pathway and modulating intestinal flora in APP/PS1 mice

Alzheimer's disease (AD) has become an important public health issue worldwide. p-Coumaric acid (CA) and lactoferrin (Lf) possessed antioxidant, anti-inflammatory, and anti-AD activities. Herein, we hypothesized that a combination treatment of CA and Lf would synergistically improve AD symptoms...

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Bibliographic Details
Main Authors: Yan Zhou, Yitian Sun, Hui Guo, Yanzi Liang, Siyuan Zhu, Yu Sha, Zhongxiao Wan, Jiaying Xu, Jianrong Jiang, Liqiang Qin, Yunhong Li
Format: Article
Language:English
Published: Tsinghua University Press 2025-07-01
Series:Food Science and Human Wellness
Subjects:
p-coumaric acid and lactoferrin combination
cognitive deficits
c/ebpβ/aep pathway
Online Access:https://www.sciopen.com/article/10.26599/FSHW.2024.9250164
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https://www.sciopen.com/article/10.26599/FSHW.2024.9250164

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