BHLHE40 contributes to allergic asthma progression in mice through NRTN downregulation in macrophages
Abstract Alternatively activated M2-like macrophages have a profound impact on asthma pathogenesis. Basic Helix-Loop-Helix Family Member E40 (BHLHE40), a dimeric transcriptional factor, plays a key regulation in macrophage functions. Here we show that ovalbumin (OVA)-challenged mice exhibited greate...
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| Main Authors: | Bing Dai, Li Chen, Xiaowen Li, Qianlan Zhou, Qinzhen Zhang, Lina Han, Wenxin Shen, Qing Chang, Yuhong Zhao, Si Liu, Lishen Shan |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-06-01
|
| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-025-08288-1 |
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