Robust quantitative assessment of collagen fibers with picrosirius red stain and linearly polarized light as demonstrated on atherosclerotic plaque samples.

Collagen is an important component in maintaining structural integrity and functionality of tissues and is modulated in various biological processes. Its visualization and possible quantification using histopathological stains can be important for understanding disease progression or therapeutic res...

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Bibliographic Details
Main Authors: Cherry Greiner, Stephanie Grainger, Samantha Farrow, Alena Davis, Jimmy L Su, Matthew D Saybolt, Robert Wilensky, Sean Madden, Stephen T Sum
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0248068&type=printable
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