Translating medication effects for alcohol use disorder across preclinical, human laboratory, and clinical trial outcomes using meta-analysis
Abstract Animal models are used for preliminary testing of novel compounds for alcohol use disorder (AUD). However, it is unclear whether early efficacy in preclinical models reliably predicts efficacy in human laboratory and clinical trials. We searched the literature for medications tested for AUD...
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| Main Authors: | Steven J. Nieto, Suzanna Donato, Han Du, Lindsay R. Meredith, Wave-Ananda Baskerville, Kaitlin R. McManus, Molly Magill, Marcelo F. Lopez, Howard C. Becker, Lara A. Ray |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2025-07-01
|
| Series: | Translational Psychiatry |
| Online Access: | https://doi.org/10.1038/s41398-025-03473-6 |
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