Alkaloid-rich extract of jujube seed regenerate the antiproliferative effect of paclitaxel on paclitaxel-resistant MDA-MB-231 breast cancer cell line in 2D and 3D cultures

Alkaloid-rich extract of jujube seed regenerate the antiproliferative effect of paclitaxel on paclitaxel-resistant MDA-MB-231 breast cancer cell line in 2D and 3D cultures

Introduction: Cancer is the second leading cause of death globally, and among all types of cancer, triple-negative breast cancer (TNBC) has one of the worst prognoses. The repeated use of chemotherapeutic drugs often leads to drug resistance, complicating treatment outcomes. This study aimed to inve...

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Main Authors: Emran Habibi, Amin Sepehrara, Hesamoddin Arabnozari, Fariborz Sharifianjazi, Seyed Ehsan Enderami, Satyajit D. Sarker, Hadi Hassannia, Lutfun Nahar
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Journal of Agriculture and Food Research
Subjects:
Alkaloid-rich extract
Breast cancer
Ziziphus Jujuba
MDA-MB-231 Cell line
Paclitaxel
Online Access:http://www.sciencedirect.com/science/article/pii/S2666154324004757
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