A novel lncRNA-hidden polypeptide regulates malignant phenotypes and pemetrexed sensitivity in A549 pulmonary adenocarcinoma cells

A novel lncRNA-hidden polypeptide regulates malignant phenotypes and pemetrexed sensitivity in A549 pulmonary adenocarcinoma cells

Abstract The advance of high-throughput sequencing enhances the discovery of short ORFs embedded in long non-coding RNAs (lncRNAs). Here, we uncovered the production and biological activity of lncRNA-hidden polypeptides in lung adenocarcinoma (LUAD). In the present study, bioinformatics was used to...

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Bibliographic Details
Main Authors: Xiaobing Han, Liangxin Chen, Peng Sun, Xiuqing Wang, Qian Zhao, Lingfeng Liao, Dejin Lou, Nan Zhou, Yujun Wang
Format: Article
Language:English
Published: Springer 2024-02-01
Series:Amino Acids
Subjects:
NSCLC
lncRNA-hidden polypeptides
Short ORFs
LINC00954-ORF
PEM resistance
Online Access:https://doi.org/10.1007/s00726-023-03361-7
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https://doi.org/10.1007/s00726-023-03361-7

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