Conversion therapy with chemoimmunotherapy induced pCR in a stage IV lung squamous cell carcinoma patient harboring EGFR exon 20 insertion

Conversion therapy with chemoimmunotherapy induced pCR in a stage IV lung squamous cell carcinoma patient harboring EGFR exon 20 insertion

This case study details an innovative conversion therapy strategy in a 58-year-old Asian male with baseline stage cT4N1M1b advanced lung squamous cell carcinoma (SCC) harboring a rare EGFR exon 20 insertion mutation with concurrent high PD-L1 expression who achieved a pathologic complete response (p...

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Bibliographic Details
Main Authors: Mingjin Xu, Xingfa Huo, Chuantao Zhang, Xuchen Zhang, Huiyun Wang, Hongmin Yang, Nan Ge, Yongjie Wang, Helei Hou
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Human Vaccines & Immunotherapeutics
Subjects:
Conversion therapy
EGFR exon 20 inserted non-small cell lung cancer
immune checkpoint blockade
pathological complete response
case report
Online Access:https://www.tandfonline.com/doi/10.1080/21645515.2024.2431384
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https://www.tandfonline.com/doi/10.1080/21645515.2024.2431384

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