Inhibitory basal ganglia nuclei differentially innervate pedunculopontine nucleus subpopulations and evoke differential motor and valence behaviors
The canonical basal ganglia model predicts that the substantia nigra pars reticulata (SNr) will inhibit locomotion and the globus pallidus externa (GPe) will enhance it. In mice, we use in vivo optogenetics to show that the GPe exerts non-canonical effects on locomotion while the SNr has no gross mo...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
eLife Sciences Publications Ltd
2025-08-01
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| Series: | eLife |
| Subjects: | |
| Online Access: | https://elifesciences.org/articles/102308 |
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