Evaluation of Safety, Immunogenicity and Cross-Reactive Immunity of OVX836, a Nucleoprotein-Based Universal Influenza Vaccine, in Older Adults

Evaluation of Safety, Immunogenicity and Cross-Reactive Immunity of OVX836, a Nucleoprotein-Based Universal Influenza Vaccine, in Older Adults

<b>Background/Objectives:</b> In a Phase 2a, double-blind, placebo-controlled study including healthy participants aged 18–55 years, OVX836, a nucleoprotein (NP)-based candidate vaccine, previously showed a good safety profile, a robust immune response (both humoral and cellular) and a p...

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Main Authors: Bart Jacobs, Isabel Leroux-Roels, Jacques Bruhwyler, Nicola Groth, Gwenn Waerlop, Yorick Janssens, Jessika Tourneur, Fien De Boever, Azhar Alhatemi, Philippe Moris, Alexandre Le Vert, Geert Leroux-Roels, Florence Nicolas
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Vaccines
Subjects:
influenza
universal vaccine
Phase 2a
healthy participants
older adults
cross-reactivity
Online Access:https://www.mdpi.com/2076-393X/12/12/1391
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