Proteolytic Activity Inhibition in Gingival Fluid by Cysteine Protease Inhibitors Obtained from Egg White and <i>Fallopia japonica</i> Extract: An In Vitro Study

Proteolytic Activity Inhibition in Gingival Fluid by Cysteine Protease Inhibitors Obtained from Egg White and <i>Fallopia japonica</i> Extract: An In Vitro Study

<b>Background/Objectives</b>: Gingipains produced by <i>P. gingivalis</i> have been shown to be directly related to periodontal tissue degradation and are significant molecular targets in therapy of periodontitis. Blocking the activity of these enzymes should reduce survival...

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Main Authors: Maciej Siewiński, Maciej Dobrzyński, Krzysztof Gołąb, Maciej Janeczek, Łukasz Nieradko, Barbara Bażanów, Andrzej Rapak, Marius Boariu, Stefan-Ioan Stratul, Alla Belova, Sorina Mihaela Solomon, Renata Samulak, Monika Machoy
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Biomedicines
Subjects:
cysteine peptidases
cystatins
periodontitis
Online Access:https://www.mdpi.com/2227-9059/13/7/1545
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