Unveiling the role of Ndrg1 gene on the oxidative stress induction behind the anticancer potential of styrylquinazoline derivatives
Abstract This work presents a multifaceted mechanism of the anticancer action of a 2-styrylquinazoline derivative. Extensive analysis of various aspects related to tyrosine kinase inhibition and effects on cellular targets at both the gene and protein levels revealed the potential of this IS20 compo...
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| Main Authors: | Katarzyna Malarz, Michał Kuczak, Patryk Rurka, Patrycja Rawicka, Anna Boguszewska-Czubara, Josef Jampilek, Jacek Mularski, Robert Musiol, Anna Mrozek-Wilczkiewicz |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-05-01
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| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-025-99277-1 |
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