The thymic microenvironment gradually modulates the phenotype of thymus‐homing peripheral conventional dendritic cells

Abstract Background & Aims Thymic conventional dendritic cells (t‑DCs) are crucial for the development of T cells. A substantial fraction of t‑DCs originates extrathymically and migrates to the thymus. Here, these cells contribute to key processes of central tolerance like the clonal deletion of...

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Bibliographic Details
Main Authors: Susanne Herppich, Michael Beckstette, Jochen Huehn
Format: Article
Language:English
Published: Wiley 2022-02-01
Series:Immunity, Inflammation and Disease
Subjects:
Online Access:https://doi.org/10.1002/iid3.559
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