Metabolomic signature of pediatric diabetic ketoacidosis: key metabolites, pathways, and panels linked to clinical variables
Abstract Background Diabetic ketoacidosis (DKA) is a serious complication of type 1 diabetes (T1D), arising from relative insulin deficiency and leading to hyperglycemia, ketonemia, and metabolic acidosis. Early detection and treatment are essential to prevent severe outcomes. This pediatric case–co...
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| Main Authors: | Paolo Spagnolo, David Tweddell, Enis Cela, Mark Daley, Cheril Clarson, C. Anthony Rupar, Saverio Stranges, Michael Bravo, Gediminas Cepinskas, Douglas D. Fraser |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2024-12-01
|
| Series: | Molecular Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s10020-024-01046-9 |
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