Spontaneous eye blink-based machine learning for tracking clinical fluctuations in Parkinson’s disease

Spontaneous eye blink-based machine learning for tracking clinical fluctuations in Parkinson’s disease

Abstract In this uncontrolled, open-label exploratory clinical study, the authors explore the potential of blink data as a digital biomarker for estimating clinical indices of Parkinson’s disease (PD) using a machine learning approach. Blink data were collected from 20 patients with PD before and af...

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Main Authors: Noriko Nishikawa, Shin Tejima, Daiki Kamiyama, Mitsumasa Kurita, Koshi Yamamoto, Satoki Imai, Wataru Sako, Genko Oyama, Taku Hatano, Nobutaka Hattori
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:npj Parkinson's Disease
Online Access:https://doi.org/10.1038/s41531-025-01094-w
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https://doi.org/10.1038/s41531-025-01094-w

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