A strong anti-inflammatory signature revealed by liver transcription profiling of Tmprss6-/- mice.

A strong anti-inflammatory signature revealed by liver transcription profiling of Tmprss6-/- mice.

Control of systemic iron homeostasis is interconnected with the inflammatory response through the key iron regulator, the antimicrobial peptide hepcidin. We have previously shown that mice with iron deficiency anemia (IDA)-low hepcidin show a pro-inflammatory response that is blunted in iron deficie...

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Main Authors: Michela Riba, Marco Rausa, Melissa Sorosina, Davide Cittaro, Jose Manuel Garcia Manteiga, Antonella Nai, Alessia Pagani, Filippo Martinelli-Boneschi, Elia Stupka, Clara Camaschella, Laura Silvestri
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0069694
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https://doi.org/10.1371/journal.pone.0069694

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