<i>EGFR</i>-Mutant Lung Adenocarcinoma Cell-Derived Exosomal miR-651-5p Induces CD8+ T Cell Apoptosis via Downregulating BCL2 Expression

<b>Background</b>: The efficacy of programmed cell death 1 (PD-1) or ligand 1 (PD-L1) inhibitors in epidermal growth factor receptor (<i>EGFR</i>)-mutant non-small cell lung cancer (NSCLC) patients is not satisfactory. Studies have indicated that the ratio of CD8+ tumor infil...

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Bibliographic Details
Main Authors: Chao Zhao, Lei Cheng, Aiwu Li, Haowei Wang, Xuefei Li, Jun Xu
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Biomedicines
Subjects:
Online Access:https://www.mdpi.com/2227-9059/13/2/482
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