Therapeutic potential of tumor-associated neutrophils: dual role and phenotypic plasticity

Abstract Neutrophils are the first line of defense in nonspecific immunity (innate immunity) and interact with other immune cells to participate in specific defense mechanisms (adaptive immunity). Studies have shown that the tumor microenvironment (TME) mediates tumor development and recruits neutro...

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Bibliographic Details
Main Authors: Yanting Zhou, Guobo Shen, Xikun Zhou, Jing Li
Format: Article
Language:English
Published: Nature Publishing Group 2025-06-01
Series:Signal Transduction and Targeted Therapy
Online Access:https://doi.org/10.1038/s41392-025-02242-7
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