Prosit-XL: enhanced cross-linked peptide identification by fragment intensity prediction to study protein interactions and structures

Abstract It has been shown that integrating peptide property predictions such as fragment intensity into the scoring process of peptide spectrum match can greatly increase the number of confidently identified peptides compared to using traditional scoring methods. Here, we introduce Prosit-XL, a rob...

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Bibliographic Details
Main Authors: Mostafa Kalhor, Cemil Can Saylan, Mario Picciani, Lutz Fischer, Falk Boudewijn Schimweg, Joel Lapin, Juri Rappsilber, Mathias Wilhelm
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-61203-4
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