Time series differences in coagulopathy in mechanically ventilated COVID-19 and bacterial pneumonia patients: a nationwide observational study in Japan

Time series differences in coagulopathy in mechanically ventilated COVID-19 and bacterial pneumonia patients: a nationwide observational study in Japan

Abstract Background Severe acute respiratory syndrome coronavirus 2 infection causes systemic immune overresponse (cytokine storm), which can lead to microthrombi and dysfunction of coagulation such as disseminated intravascular coagulation (DIC) of sepsis. Coronavirus disease 2019 (COVID-19) coagul...

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Main Authors: Ryo Hisamune, Kazuma Yamakawa, Noritaka Ushio, Katsunori Mochizuki, Tadashi Matsuoka, Yutaka Umemura, Mineji Hayakawa, Hirotaka Mori, Akira Endo, Takayuki Ogura, Atsushi Hirayama, Hideo Yasunaga, Takashi Tagami, Kohji Okamoto, Akira Takasu
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Thrombosis Journal
Subjects:
Antithrombin activity
COVID-19
Disseminated intravascular coagulation
Sepsis
Thrombocytopenia
Online Access:https://doi.org/10.1186/s12959-025-00747-3
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https://doi.org/10.1186/s12959-025-00747-3

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