TRIM47 promotes head and neck squamous cell carcinoma malignant progression by degrading XAF1 through ubiquitination

Summary: Tripartite motif-containing 47 (TRIM47) is a member of the TRIM family, which has E3 ligase activity and has been demonstrated to be involved in tumor development. In this work, we found that TRIM47 is highly expressed in head and neck squamous cell carcinomas (HNSCC) tissues. TRIM47 overex...

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Bibliographic Details
Main Authors: Changyun Yu, Chen Zhang, Qianqian Zhang, Cai Zhang, Jingjie Han, Jinying Li
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:iScience
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Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224028177
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