Allelic Switching of DLX5, GRB10, and SVOPL during Colorectal Cancer Tumorigenesis

Allele-specific expression (ASE) is found in approximately 20-30% of human genes. During tumorigenesis, ASE changes due to somatic alterations that change the regulatory landscape. In colorectal cancer (CRC), many chromosomes show frequent gains or losses while homozygosity of chromosome 7 is rare....

Full description

Saved in:
Bibliographic Details
Main Authors: Arnoud Boot, Jan Oosting, Saskia Doorn, Sarah Ouahoud, Marina Ventayol Garcia, Dina Ruano, Hans Morreau, Tom van Wezel
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:International Journal of Genomics
Online Access:http://dx.doi.org/10.1155/2019/1287671
Tags: Add Tag
No Tags, Be the first to tag this record!