PIDDosome Expression and the Role of Caspase-2 Activation for Chemotherapy-Induced Apoptosis in RCCs

Background: The importance of caspase-2 activation for mediating apoptosis in cancer is not clear and seems to differ between different tumour types. Furthermore, only few data have been obtained concerning the expression of caspase-2, which can be alternatively spliced into caspase-2L and caspase-2...

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Bibliographic Details
Main Authors: Sebastian Heikaus, Igor Pejin, Helmut Erich Gabbert, Uwe Ramp, Csaba Mahotka
Format: Article
Language:English
Published: Wiley 2010-01-01
Series:Cellular Oncology
Online Access:http://dx.doi.org/10.3233/CLO-2009-0492
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