Quantitative relationship between hippocampal injury and mechanical load and body weight in closed head injury of male rats using quadratic orthogonal regression

Abstract Memory dysfunction, a common symptom following closed head impact injuries, suggests deficits in hippocampal function. This defect is thought to be related to impact strength and individual animal weight. In this study, head impact experiments were performed on male Sprague Dawley rats to e...

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Bibliographic Details
Main Authors: Peng Wang, Xuewei Song, Qiushi Wang, Jinlong Qiu, Xiyan Zhu, Tianming Yu, Hongyi Xiang, Hui Zhao
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-00108-0
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