N-terminus of Drosophila melanogaster MSL1 is critical for dosage compensation

N-terminus of Drosophila melanogaster MSL1 is critical for dosage compensation

The male-specific lethal complex (MSL), which consists of five proteins and two non-coding roX RNAs, is involved in the transcriptional enhancement of X-linked genes to compensate for the sex chromosome monosomy in Drosophila XY males compared with XX females. The MSL1 and MSL2 proteins form the het...

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Bibliographic Details
Main Authors: Valentin Babosha, Natalia Klimenko, Anastasia Revel-Muroz, Evgeniya Tikhonova, Pavel Georgiev, Oksana Maksimenko
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2024-12-01
Series:eLife
Subjects:
sex determination
RNA-protein interaction
MSL complex
transcription factor
MSL2
MSL3
Online Access:https://elifesciences.org/articles/93241
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https://elifesciences.org/articles/93241

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