Rare variants and founder effect in the Beauce region of Quebec

Abstract Founder events influenced the genetic diversity within the province of Quebec, increasing the frequency of certain rare pathogenic variants in regional populations. Some regions, such as Beauce, remain understudied despite evidence of a regional founder effect. Leveraging extensive genealog...

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Bibliographic Details
Main Authors: Mylène Gagnon, Claudia Moreau, Jasmin Ricard, Marie-Claude Boisvert, Alexandre Bureau, Michel Maziade, Simon L. Girard
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-025-08630-7
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