Ginkgo biloba attenuates complete Freund’s adjuvant-induced inflammatory pain by suppressing the NF-κB-CXCL1/CXCR2 signaling cascade in the rat spinal cord

Ginkgo biloba attenuates complete Freund’s adjuvant-induced inflammatory pain by suppressing the NF-κB-CXCL1/CXCR2 signaling cascade in the rat spinal cord

Background: Inflammatory pain is the most common type of chronic pain, and it is rapidly becoming a global health problem. Ginkgo biloba (EGb761) is a natural plant that contains several bioactive components with antioxidant and free radical scavenging properties. However, its underlying mechanism i...

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Bibliographic Details
Main Authors: Sherine Abdel Salam, Catherine S. George, Najla K. Al Abdulsalam, Ashraf M. Abdel-Moneim, Amina E. Essawy
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Redox Report
Subjects:
EGb761
inflammatory pain
free radicals
NF-κB-CXCL1/CXCR2 signaling
caspase-3
Bcl-2
Online Access:https://www.tandfonline.com/doi/10.1080/13510002.2024.2447778
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https://www.tandfonline.com/doi/10.1080/13510002.2024.2447778

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