Shifting landscapes: dynamic changes from pro- to anti-inflammatory leukocyte phenotype in myocardial ischemia/reperfusion injury

Shifting landscapes: dynamic changes from pro- to anti-inflammatory leukocyte phenotype in myocardial ischemia/reperfusion injury

BackgroundThe temporal and spatial dynamics of platelet–leukocyte complex (PLC) formation in myocardial ischemia reperfusion injury (I/R injury) are still ill defined.AimTo investigate the kinetics and spatial differences of platelet-monocyte (PMC) and platelet-neutrophil (PNC) complex formation ove...

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Bibliographic Details
Main Authors: Pia Kröning, Maximilian Mauler, Nancy Schanze, Katharina Naber, Daniela Stallmann, Daniel Duerschmied, Dirk Westermann, Nadine Gauchel
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
ischemia reperfusion injury
myocardial infarction
neutrophils
monocytes
platelet-leukocyte-complexes
inflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2025.1596538/full
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https://www.frontiersin.org/articles/10.3389/fcvm.2025.1596538/full

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