An In vitro investigation of Lactobacillus plantarum F4 Strain’s Anti-sickling and Fetal Hemoglobin Inducing Effects on Sickled Erythrocytes

An In vitro investigation of Lactobacillus plantarum F4 Strain’s Anti-sickling and Fetal Hemoglobin Inducing Effects on Sickled Erythrocytes

Sickle cell disease (SCD) is a blood illness occurs due to point mutation in the β-globin gene and leads to serious health problems. The aim of the study was to assess probiotic Lactobacillus plantarum F4’s (L. plantarum F4) capacity to induce fetal hemoglobin (HbF) synthesis and anti-sickling effec...

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Bibliographic Details
Main Authors: Firdosh Shah, Saloni R. Shah, Aasruti S. Pramanik, Prasant Kumar, Naresh C. Laddha, Mitesh Dwivedi
Format: Article
Language:English
Published: Journal of Pure and Applied Microbiology 2025-03-01
Series:Journal of Pure and Applied Microbiology
Subjects:
sickle cell disease (scd)
sickled erythrocytes
l. plantarum
anti-sickling activity
fetal hemoglobin (hbf)
hydroxyurea
Online Access:https://microbiologyjournal.org/an-in-vitro-investigation-of-lactobacillus-plantarum-f4-strains-anti-sickling-and-fetal-hemoglobin-inducing-effects-on-sickled-erythrocytes/
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https://microbiologyjournal.org/an-in-vitro-investigation-of-lactobacillus-plantarum-f4-strains-anti-sickling-and-fetal-hemoglobin-inducing-effects-on-sickled-erythrocytes/

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