α9 Nicotinic Acetylcholine Receptor Promotes Tumor Proliferation and Suppresses Ferroptosis in Triple-Negative Breast Cancer

α9 Nicotinic Acetylcholine Receptor Promotes Tumor Proliferation and Suppresses Ferroptosis in Triple-Negative Breast Cancer

Breast cancer is a major global health burden with the highest incidence in women, and triple-negative breast cancer (TNBC) stands out as the most malignant subtype. Effective therapeutic targets are urgently needed to develop new therapies for TNBC. Nicotinic acetylcholine receptor is a ligand-gate...

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Bibliographic Details
Main Authors: Xiaoli Feng, Yuxi Tian, Xijun Guo, Josh Haipeng Lei, Jiaqi Yu, Chenglong Zheng, Mingyue Chen, Ren-Bo Ding, Hang Fai Kwok, Sulan Luo, Jiaolin Bao
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Biomolecules
Subjects:
nicotinic acetylcholine receptor
α9 nAChR
CHRNA9
triple-negative breast cancer
ferroptosis
proliferation
Online Access:https://www.mdpi.com/2218-273X/15/6/835
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