Influence of Constipation in the Behavior of Circulating Alpha- and Beta-CGRP Levels in Chronic/High-Frequency Migraine Patients After CGRP Monoclonal Antibodies

Influence of Constipation in the Behavior of Circulating Alpha- and Beta-CGRP Levels in Chronic/High-Frequency Migraine Patients After CGRP Monoclonal Antibodies

<b>Background/Objectives</b>: Migraines contain neurological and gastrointestinal manifestations. The first specific migraine preventive drugs, CGRP monoclonal antibodies (mAbs), though efficacious and very well-tolerated in general, induce constipation as their main adverse event. Our g...

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Bibliographic Details
Main Authors: Gabriel Gárate, Marcos Polanco, Jorge Madera, María Muñoz-San Martín, Marta Pascual-Mato, Vicente González-Quintanilla, Julio Pascual
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Biomedicines
Subjects:
alpha-CGRP
beta-CGRP
chronic migraine
constipation
CGRP monoclonal antibodies
high-frequency episodic migraine
Online Access:https://www.mdpi.com/2227-9059/13/5/1254
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