The SpasT-SCI-T trial protocol: Investigating calpain-mediated sodium channel fragments as biomarkers for traumatic CNS injuries and spasticity prediction.

Spinal cord injury and traumatic brain injury are major causes of long-term disability and are often complicated by spasticity, a motor disorder characterized by increased muscle tone and exaggerated reflexes that significantly impair quality of life. Current diagnostic methods lack the sensitivity...

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Bibliographic Details
Main Authors: Guillaume Baucher, Sylvie Liabeuf, Cécile Brocard, Aurélie Ponz, Karine Baumstarck, Lucas Troude, Marc Leone, Pierre-Hugues Roche, Frédéric Brocard
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0319635
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