Janus piezoelectric adhesives regulate macrophage TRPV1/Ca2+/cAMP axis to stimulate tendon-to-bone healing by multi-omics analysis

Janus piezoelectric adhesives regulate macrophage TRPV1/Ca2+/cAMP axis to stimulate tendon-to-bone healing by multi-omics analysis

Piezoelectric stimulation has garnered substantial interest as a promising strategy for tissue regeneration. However, studies investigating its impact on tendon-to-bone healing characterized by fibrocartilage remain scarce. Moreover, there are considerable technical challenges in achieving minimally...

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Bibliographic Details
Main Authors: Moran Huang, Wan Li, Yaying Sun, Jize Dong, Chaojing Li, Henjie Jia, Yongjie Jiao, Lu Wang, Shanxing Zhang, Fujun Wang, Jiwu Chen
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2025-08-01
Series:Bioactive Materials
Subjects:
Piezoelectric biomaterials
Tendon-to-bone healing
Immunomodulation
Asymmetric adhesive hydrogel
TRP channels
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X25001392
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