Preclinical Development and Phase I Study of ZSYY001, a Polymeric Micellar Paclitaxel for Advanced Solid Tumor

ABSTRACT Purpose A novel paclitaxel delivery system has the potential to avoid the side effects associated with Cremophor EL and thus enhance therapeutic efficacy. Here, we report the results of a preclinical and phase I clinical study investigating ZSYY001, a nanoparticle formulation of polymeric m...

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Bibliographic Details
Main Authors: Ge Gao, Pei Shu, Youzhen Tan, Tongsen Zheng, Wenmao Fan, Luding Lu, Huan Zhou, Zishu Wang, Ling Liu, Zhiqiang Liu, Yongsheng Wang
Format: Article
Language:English
Published: Wiley 2025-07-01
Series:Cancer Medicine
Online Access:https://doi.org/10.1002/cam4.71039
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