The assessment of the cytotoxic activity of 2-(1,1-dimethyl-1H-benzo[e]indolin-2-yl)-5,6,7-trichloro-1,3-tropolone against the human glioblastoma U87 MG cell line

The assessment of the cytotoxic activity of 2-(1,1-dimethyl-1H-benzo[e]indolin-2-yl)-5,6,7-trichloro-1,3-tropolone against the human glioblastoma U87 MG cell line

Purpose of the study. To study the cytotoxic effect of 2-(1,1-dimethyl-1H-benzo[e]indolin-2-yl)-5,6,7-trichloro-1,3-tropolone (JO-122 (2)) on the U87 MG cell line.Materials and methods. The investigation of the cytotoxic effect of synthesized tropolone JO-122 (2) was performed using the standard MTT...

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Bibliographic Details
Main Authors: D. V. Khodakova, N. S. Kuznetsova, S. Yu. Filippova, A. S. Goncharova, A. V. Galina, S. V. Gurova, E. A. Gusakov, Yu. A. Sayapin, E. E. Rostorguev
Format: Article
Language:Russian
Published: ANO "Perspective of oncology" 2025-06-01
Series:Южно-Российский онкологический журнал
Subjects:
glioblastoma
tropolone
u87 glioblastoma cell line
mtt assay
cytotoxicity assay
Online Access:https://www.cancersp.com/jour/article/view/317
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