Exogenous Ubiquitin Differentially Modulates the Phenotype and Function of M1 and M2 Macrophages

Background: Unresolved inflammation is a major predictor of heart failure following myocardial infarction. Exogenous ubiquitin (eUB) is shown to decrease inflammatory response and confer cardioprotection in mice 3 days post-ischemia/reperfusion (I/R) injury. Here, we hypothesized that eUB differenti...

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Bibliographic Details
Main Authors: Paige L. Shook, Hui Wang-Heaton, Jared L. Casteel, Suman Dalal, Mahipal Singh, Valentin Yakubenko, Krishna Singh
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Cells
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Online Access:https://www.mdpi.com/2073-4409/14/12/879
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