Synthetic and Functional Engineering of Bacteriophages: Approaches for Tailored Bactericidal, Diagnostic, and Delivery Platforms

Synthetic and Functional Engineering of Bacteriophages: Approaches for Tailored Bactericidal, Diagnostic, and Delivery Platforms

Bacteriophages (phages), the most abundant biological entities on Earth, have long served as both model systems and therapeutic tools. Recent advances in synthetic biology and genetic engineering have revolutionized the capacity to tailor phages with enhanced functionality beyond their natural capab...

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Bibliographic Details
Main Authors: Ola Alessa, Yoshifumi Aiba, Mahmoud Arbaah, Yuya Hidaka, Shinya Watanabe, Kazuhiko Miyanaga, Dhammika Leshan Wannigama, Longzhu Cui
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Molecules
Subjects:
bacteriophage engineering
synthetic biology
phage assembly and rebooting
phage recombineering
CRISPR-Cas systems
retron-mediated editing
Online Access:https://www.mdpi.com/1420-3049/30/15/3132
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