Differential Role of Rapamycin and Torin/KU63794 in Inflammatory Response of 264.7 RAW Macrophages Stimulated by CA-MRSA

Background. Rapamycin suppresses the RAW264.7 macrophage mediated inflammatory response but in lower doses induces it. In the present study, we tested the suppression of the inflammatory response in the presence of mTOR 1 and 2 inhibitors, Torin and KU63794. Methods. RAW264.7 cells were stimulated...

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Bibliographic Details
Main Authors: Rebekah K. H. Shappley, Thomas Spentzas
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:International Journal of Inflammation
Online Access:http://dx.doi.org/10.1155/2014/560790
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