Leonurine (SCM-198) exerts protective effects on pancreatic β-cells in type 1 diabetes by modulating the Bax/Bcl-2/Caspase-3 signaling pathway

Abstract Background Type 1 diabetes mellitus (T1DM) is a disease marked by insulin deficiency and hyperglycemia, resulting from the destruction of pancreatic β-cells. The progression of T1DM is significantly influenced by oxidative stress and apoptosis. Natural compounds are highly effective in the...

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Bibliographic Details
Main Authors: Zhiqi Li, XiaoRan Liu, FuJiang Wen, WenGuo Jiang, ZhenHong Xia
Format: Article
Language:English
Published: BMC 2025-08-01
Series:BMC Complementary Medicine and Therapies
Subjects:
Online Access:https://doi.org/10.1186/s12906-025-05051-1
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